CBD for anxiety and depressive disorders.
Anxiety surrounds us. Consumes some of us. We need a better way, a safer way to help us cope than what modern medicine offers.
CBD is safe, and has been shown to have few negative side effects. It’s well tolerated up to 1500 mg/day, with people showing no psycho motor slowing, negative mood effects or vital sign abnormalities (Bergamaschi et al, 2013). It is not addictive, and there is no fear of withdrawl symptoms.
Now the naysayers are happy to remind everyone that there are not enough studies to confirm the findings. They’ll also point out FDC has not approved this “drug”, and… there is no single way to dose this “drug”.
On the other hand, you will also hear from friends and family that CBD has changed their lives.
Some interesting Data
In a 2015 study  to determine CBDs potential as a treatment for anxiety related disorders, it was found that existing pre-clinical evidence strongly supports CBD as a treatment for the following conditions:
- generalized anxiety disorder
- panic disorder
- social anxiety disorder
- obsessive-compulsive disorder
- post-traumatic stress disorder
Now, there are plenty of pharmaceuticals ready to deal with these issues, right?
Some of these include serotonin reuptake inhibitors (SRIs and SSRIs), benzodiazepines, antidepressant drugs… as well as anticonvulsants and antipsychotics. However most, if not all of these options, have a host of side effects; with some being very serious. Additionally some may cause addition and withdrawal symptoms if you stop taking them.
On the other hand, CBD has been found to have no detrimental side effects or withdrawl symptoms.
Cannabidiol as a Potential Treatment for Anxiety Disorders. https://www.ncbi.nlm.nih.gov/pubmed/26341731
How is that possible?
CBD has been found to interact with receptors known to regulate fear and anxiety behaviors. (2)
Similar to SSRIs, CBD may boost signaling through serotonin receptors.
In an animal study, Spanish researchers found that CBD enhances 5-HT1A transmissions and may affect serotonin faster than SSRIs. Researchers noted:
“The fast onset of antidepressant action of CBD and the simultaneous anxiolytic (anti-anxiety) effect would solve some of the main limitations of current antidepressant therapies.”
Yet another way CBD helps is by promoting neurogenesis. This process is literally rebuilding neurons in the hippocampus.(3) This is interesting as brain scans of people suffering from depression or anxiety often show a smaller hippocampus. Successful treatment is linked to new neurons being generated in this important area of the brain.
While more research, on humans and animals needs to be done, evidence is mounting that CBD can be used effectively to treat anxiety disorders, alone or in conjuction with other pharmacuticals. It is being shown that CBD is effective and carries a much better safely profile than what is currently being prescribed by modern medicine.
For more information on CBD itself, check out our What Is CBD page?